Issue 20, 2022
From the journal:

Chemical Communications

An ultrasound activated cyanine-rhenium(i) complex for sonodynamic and gas synergistic therapy†

Jiayi Zhu,ab   Ai Ouyang,a   Jiaqi He,c   Juan Xie,a   Samya Banerjee, ORCID logo *d   Qianling Zhang ORCID logo a  and  Pingyu Zhang ORCID logo *a  

* Corresponding authors

a College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, China
E-mail: p.zhang6@szu.edu.cn

b College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, China

c School of Chemistry and Chemical Engineering, Shanghai Jiaotong University, Shanghai, China

d Department of Chemistry, Indian Institute of Technology (BHU), Varanasi, UP-221005, India
E-mail: samya.chy@itbhu.ac.in

Abstract

A novel cyanine-rhenium(I) tricarbonyl complex is developed as a potent sonosensitizer and sono-activatable CO-releasing agent for synergistic sonodynamic therapy and CO gas therapy of cancer. The complex induced ferroptosis as the mode of cell death.

Graphical abstract: An ultrasound activated cyanine-rhenium(i) complex for sonodynamic and gas synergistic therapy

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Article information

DOI
https://doi.org/10.1039/D1CC06769A
Article type
Communication
Submitted
09 Dec 2021
Accepted
09 Feb 2022
First published
11 Feb 2022

Chem. Commun., 2022,58, 3314-3317

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An ultrasound activated cyanine-rhenium(I) complex for sonodynamic and gas synergistic therapy

J. Zhu, A. Ouyang, J. He, J. Xie, S. Banerjee, Q. Zhang and P. Zhang, Chem. Commun., 2022, 58, 3314 DOI: 10.1039/D1CC06769A

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