Issue 63, 2022
From the journal:

Chemical Communications

Probing the cell delivery of synthetic diubiquitin chains†

Shaswati Mandal ORCID logo a  and  Ashraf Brik ORCID logo *a  

* Corresponding authors

a Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa, Israel
E-mail: abrik@technion.ac.il

Abstract

In this study, the live-cell delivery of structurally different synthetic diubiquitin chains was examined. We found that the combination of structural variations of the Ub chains (intrinsic factors); nature of CPP and CPP-protein linkage (extrinsic factors) influence their delivery.

Graphical abstract: Probing the cell delivery of synthetic diubiquitin chains

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Article information

DOI
https://doi.org/10.1039/D2CC02476D
Article type
Communication
Submitted
02 May 2022
Accepted
06 Jun 2022
First published
15 Jul 2022
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2022,58, 8782-8785

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Probing the cell delivery of synthetic diubiquitin chains

S. Mandal and A. Brik, Chem. Commun., 2022, 58, 8782 DOI: 10.1039/D2CC02476D

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