Issue 81, 2022
From the journal:

Chemical Communications

Self-assembly of an MRI responsive agent under physiological conditions provides an extended time window for in vivo imaging†

Nishanth D. Tirukoti,a   Liat Avram, ORCID logo b   Reut Mashiach,a   Hyla Allouche-Arnona  and  Amnon Bar-Shir ORCID logo *a  

* Corresponding authors

a Department of Molecular Chemistry and Materials Science, Weizmann Institute of Science, Rehovot 7610001, Israel
E-mail: amnon.barshir@weizmann.ac.il

b Department of Chemical Research Support, Weizmann Institute of Science, Rehovot 7610001, Israel

Abstract

An MRI-responsive agent that spontaneously self-assembles to a large supramolecular structure under physiological conditions was designed. The obtained assembly provides an extended time window for in vivo studies, as demonstrated for a fluorine-19 probe constructed to sense Zn2+ with 19F-iCEST MRI, in the future.

Graphical abstract: Self-assembly of an MRI responsive agent under physiological conditions provides an extended time window for in vivo imaging

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Article information

DOI
https://doi.org/10.1039/D2CC03126D
Article type
Communication
Submitted
09 Jul 2022
Accepted
15 Sep 2022
First published
15 Sep 2022
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2022,58, 11410-11413

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Self-assembly of an MRI responsive agent under physiological conditions provides an extended time window for in vivo imaging

N. D. Tirukoti, L. Avram, R. Mashiach, H. Allouche-Arnon and A. Bar-Shir, Chem. Commun., 2022, 58, 11410 DOI: 10.1039/D2CC03126D

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