Issue 2, 2022
From the journal:

Nanoscale Advances

Purification of quantum dot-based bioprobes with a salting out strategy†

Zhi-Liang Chen ORCID logo a  and  Jia-quan Xu ORCID logo *b  

* Corresponding authors

a School of Pharmacy, Shaoyang University, Shaoyang, P. R. China

b Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, East China University of Technology, Nanchang, China
E-mail: jiaquan_xu@foxmail.com
Tel: +86-739-5308282

Abstract

A salting out strategy is reported for purification of IgG-conjugated QD (IgG-QD) bioprobes. Adding NaCl can precipitate free IgG selectively, while the IgG-QD maintains good colloidal stability. The dynamic light scattering technique reveals that this is due to the relatively positive zeta potential of free IgG than that of the IgG-QD.

Graphical abstract: Purification of quantum dot-based bioprobes with a salting out strategy

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Article information

DOI
https://doi.org/10.1039/D1NA00569C
Article type
Communication
Submitted
23 Jul 2021
Accepted
08 Dec 2021
First published
04 Jan 2022
This article is Open Access
Creative Commons BY license

Nanoscale Adv., 2022,4, 393-396

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Purification of quantum dot-based bioprobes with a salting out strategy

Z. Chen and J. Xu, Nanoscale Adv., 2022, 4, 393 DOI: 10.1039/D1NA00569C

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