Issue 13, 2022

A silver-functionalized metal–organic framework with effective antibacterial activity

Abstract

Ag nanoparticles have attracted wide research interest due to their broad spectrum of antimicrobial activities. However, Ag nanoparticles are prone to aggregate, which decreases the accessible surface area and diminishes the antibacterial activity. Herein, a metal–organic framework with alkene-functional groups was constructed and postsynthetically modified with Ag(I) for antibacterial applications. The Ag@Zn-MOF exhibits high antibacterial activity toward E. coli and S. aureus, which reaches ∼100% bacterial reduction at a concentration as low as 25 μgMOF cm−3 (corresponding to 1.7 μgAg cm−3). These results demonstrated that Ag(I)-modified MOFs could act as effective antimicrobial agents with potential applications in food and healthcare.

Graphical abstract: A silver-functionalized metal–organic framework with effective antibacterial activity

Supplementary files

Article information

Article type
Communication
Submitted
28 Dec 2021
Accepted
28 Feb 2022
First published
28 Feb 2022

New J. Chem., 2022,46, 5922-5926

A silver-functionalized metal–organic framework with effective antibacterial activity

Y. Wu, P. Zhao, B. Jia, Z. Li, S. Yuan and C. Li, New J. Chem., 2022, 46, 5922 DOI: 10.1039/D1NJ06183F

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