A double-triggered self-immolative spacer for increased selectivity of molecular release†
Ludovic
Jullien 
*b
and
Frédéric
Schmidt
*c
*b
and
Frédéric
Schmidt
*c
Abstract
A self-immolative spacer based on dissymmetrical N,N′-bis-carbamate aniline is introduced to liberate a substrate from a precursor after dual activation. The proof of principle of its exclusive selectivity for substrate liberation has been conducted on a profluorophore.
- This article is part of the themed collection: Chemical Biology in OBC
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