Herein, we report the development of a novel route to tricyclic lactam products via a facile aza-[4 + 2] cycloaddition of catalytically generated acyliminium ions. Employing a Ca(NTf2)2/nBu4NPF6 catalyst system in low loadings, a range of diverse fused ring systems can be synthesised in predominantly good yields.
![Graphical abstract: Aza-[4 + 2] cycloadditions employing catalytically derived N-acyliminium ions](/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=D2OB01663J&imageInfo.ImageIdentifier.Year=2022)
N. J. Owen and M. G. McLaughlin, Org. Biomol. Chem., 2022, 20, 8209 DOI: 10.1039/D2OB01663J
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