Concentrated polymer brush-modified cellulose nanofibers promote chondrogenic differentiation of human mesenchymal stem cells by controlling self-assembly

Punnida Nonsuwan; Nanami Nishijima; Keita Sakakibara; Tadashi Nakaji-Hirabayashi; Chiaki Yoshikawa

doi:10.1039/D1TB02307A

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Concentrated polymer brush-modified cellulose nanofibers promote chondrogenic differentiation of human mesenchymal stem cells by controlling self-assembly†

Punnida Nonsuwan,‡^a Nanami Nishijima,‡^ab Keita Sakakibara,

*^c Tadashi Nakaji-Hirabayashi

*^abd and Chiaki Yoshikawa

*^a

Author affiliations

* Corresponding authors

^a Research Center for Functional Materials, National Institute for Materials Science (NIMS), Tsukuba, Ibaraki 305-0047, Japan
E-mail: yoshikawa.chiaki@nims.go.jp

^b Faculty of Engineering, Academic Assembly, University of Toyama, 3190 Gofuku, Toyama, Toyama 930-8555, Japan

^c Research Institute for Sustainable Chemistry, National Institute of Advanced Industrial Science and Technology (AIST), 3-11-32 Kagamiyama, Higashi-hiroshima, Hiroshima 739-0046, Japan

^d Graduate School of Innovative Life Science, University of Toyama, 2630 Sugitani, Toyama, Toyama 930-0194, Japan

Abstract

In order to develop new three-dimensional (3D) cell culture systems for articular cartilage regeneration, concentrated poly(styrene sulfonate sodium salt) brush-modified cellulose nanofibers were employed as building blocks for the self-assembly of human mesenchymal stem cells (hMSCs). Unique 3D cellular structures, such as giant spheres and sheets, were formed by controlling hMSC self-assembly.

This article is part of the themed collection: Bioinspired Surfaces Engineering for Biomaterials

Download options Please wait...

Supplementary files

Supplementary information PDF (1023K)

Article information

DOI: https://doi.org/10.1039/D1TB02307A
Article type: Communication
Submitted: 21 Oct 2021
Accepted: 11 Jan 2022
First published: 19 Jan 2022

Download Citation

J. Mater. Chem. B, 2022,10, 2444-2453

Permissions

Request permissions

Concentrated polymer brush-modified cellulose nanofibers promote chondrogenic differentiation of human mesenchymal stem cells by controlling self-assembly

P. Nonsuwan, N. Nishijima, K. Sakakibara, T. Nakaji-Hirabayashi and C. Yoshikawa, J. Mater. Chem. B, 2022, 10, 2444 DOI: 10.1039/D1TB02307A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Journal of Materials Chemistry B

Concentrated polymer brush-modified cellulose nanofibers promote chondrogenic differentiation of human mesenchymal stem cells by controlling self-assembly†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Concentrated polymer brush-modified cellulose nanofibers promote chondrogenic differentiation of human mesenchymal stem cells by controlling self-assembly

Social activity

Search articles by author

Spotlight

Advertisements