Issue 20, 2023

A near-infrared fluorescent nanoprobe for senescence-associated β-galactosidase sensing in living cells

Abstract

A near-infrared fluorescent nanoprobe based on semiconducting polymer nanoparticles (SPNs) for the detection of senescence-associated β-gal (SA-β-gal) is developed. Benefiting from the intrinsic lysosome-locating feature, this probe can be successfully used for the visualization of SA-β-gal in living cells.

Graphical abstract: A near-infrared fluorescent nanoprobe for senescence-associated β-galactosidase sensing in living cells

Supplementary files

Article information

Article type
Communication
Submitted
11 Oct 2022
Accepted
10 Feb 2023
First published
14 Feb 2023

Chem. Commun., 2023,59, 2974-2977

A near-infrared fluorescent nanoprobe for senescence-associated β-galactosidase sensing in living cells

Y. Zhao, S. Sun, Y. Lyu, M. Gao, H. Lin and C. Yang, Chem. Commun., 2023, 59, 2974 DOI: 10.1039/D2CC05550C

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