Chloroacetyl boronate N-tosylhydrazone as a versatile synthetic building block†
Abstract
Chloroacetyl boronate N-tosylhydrazone (CABT) has been synthesized as a reagent to generate a diverse range of molecular skeletons. CABT can undergo a series of transformations involving nucleophilic substitution of the chloride and coupling of the N-tosylhydrazones, followed by boryl group functionalization. We further demonstrated that this CABT reagent could enable a diversity-oriented synthesis.
- This article is part of the themed collection: 2023 Emerging Investigators