Issue 58, 2023

Sequencing for oxidative DNA damage at single-nucleotide resolution with click-code-seq v2.0

Abstract

Oxidative damage to DNA nucleotides has many cellular outcomes that could be aided by the development of sequencing methods. Herein, the previously reported click-code-seq method for sequencing a single damage type is redeveloped to enable the sequencing of many damage types by making simple changes to the protocol (i.e., click-code-seq v2.0).

Graphical abstract: Sequencing for oxidative DNA damage at single-nucleotide resolution with click-code-seq v2.0

Supplementary files

Article information

Article type
Communication
Submitted
05 Jun 2023
Accepted
26 Jun 2023
First published
27 Jun 2023

Chem. Commun., 2023,59, 8997-9000

Sequencing for oxidative DNA damage at single-nucleotide resolution with click-code-seq v2.0

S. Xiao, A. M. Fleming and C. J. Burrows, Chem. Commun., 2023, 59, 8997 DOI: 10.1039/D3CC02699J

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