Issue 68, 2023
From the journal:

Chemical Communications

A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential†

Qing-yu Ma,‡a   Xiang Li,‡a   Wei Zhou,a   Xia-fen Li,a   Yi-chen Liu,a   Gai-li Feng,a   Hongwei Tan, ORCID logo a   Yuan Zhang*ab  and  Guo-wen Xing ORCID logo *a  

* Corresponding authors

a College of Chemistry, Beijing Normal University, Beijing, China
E-mail: yuanzhang@bnu.edu.cn, gwxing@bnu.edu.cn

b Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Beijing, China

Abstract

We report a water-soluble AIEgen (TPAL) that can self-assemble into fluorescent organic nanoparticles for the ratiometric detection of mitochondrial DNA (mtDNA) parallel G-quadruplexes (G4s) with high selectivity, a low detection limit and photodynamic therapy (PDT) potential.

Graphical abstract: A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential

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Article information

DOI
https://doi.org/10.1039/D3CC02788K
Article type
Communication
Submitted
09 Jun 2023
Accepted
24 Jul 2023
First published
24 Jul 2023

Chem. Commun., 2023,59, 10287-10290

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A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential

Q. Ma, X. Li, W. Zhou, X. Li, Y. Liu, G. Feng, H. Tan, Y. Zhang and G. Xing, Chem. Commun., 2023, 59, 10287 DOI: 10.1039/D3CC02788K

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