Issue 68, 2023

A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential

Abstract

We report a water-soluble AIEgen (TPAL) that can self-assemble into fluorescent organic nanoparticles for the ratiometric detection of mitochondrial DNA (mtDNA) parallel G-quadruplexes (G4s) with high selectivity, a low detection limit and photodynamic therapy (PDT) potential.

Graphical abstract: A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential

Supplementary files

Article information

Article type
Communication
Submitted
09 Jun 2023
Accepted
24 Jul 2023
First published
24 Jul 2023

Chem. Commun., 2023,59, 10287-10290

A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential

Q. Ma, X. Li, W. Zhou, X. Li, Y. Liu, G. Feng, H. Tan, Y. Zhang and G. Xing, Chem. Commun., 2023, 59, 10287 DOI: 10.1039/D3CC02788K

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