Issue 58, 2023
From the journal:

Chemical Communications

Ratiometric photoacoustic imaging of endogenous HNO in vivo for assessing prodrug release and liver injury†

Xiaopeng Fan,*ab   Hongzhen Wang,a   Wen Yang,*b   Tianbing Ren ORCID logo *b  and  Lin Yuan ORCID logo b  

* Corresponding authors

a State Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, College of Chemistry & Materials Science, Hebei University, Baoding 071002, P. R. China
E-mail: xiaopengfan@hbu.edu.cn

b State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, P. R. China
E-mail: rentianbing@hnu.edu.cn, yangwen@hnu.edu.cn

Abstract

The effective imaging of endogenous HNO is highly crucial for pathology research and medical development due to its important pharmacological activity in biological systems. Here, a ratiometric photoacoustic probe in response to HNO was rationally developed to effectively assess HNO prodrug release and liver injury in vivo.

Graphical abstract: Ratiometric photoacoustic imaging of endogenous HNO in vivo for assessing prodrug release and liver injury

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Article information

DOI
https://doi.org/10.1039/D3CC02857G
Article type
Communication
Submitted
14 Jun 2023
Accepted
22 Jun 2023
First published
23 Jun 2023

Chem. Commun., 2023,59, 8969-8972

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Ratiometric photoacoustic imaging of endogenous HNO in vivo for assessing prodrug release and liver injury

X. Fan, H. Wang, W. Yang, T. Ren and L. Yuan, Chem. Commun., 2023, 59, 8969 DOI: 10.1039/D3CC02857G

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