Capsule self-oscillating gels showing cell-like nonthermal membrane/shape fluctuations

Abstract

A primary interest in cell membrane and shape fluctuations is establishing experimental models reflecting only nonthermal active contributions. Here we report a millimeter-scaled capsule self-oscillating gel model mirroring the active contribution effect on cell fluctuations. In the capsule self-oscillating gels, the propagating chemical signals during a Belousov–Zhabotinsky (BZ) reaction induce simultaneous local deformations in the various regions, showing cell-like shape fluctuations. The capsule self-oscillating gels do not fluctuate without the BZ reaction, implying that only the active chemical parameter induces the gel fluctuations. The period and amplitude depend on the gel layer thickness and the concentration of the chemical substrate for the BZ reaction. Our results allow for a solid experimental platform showing actively driven cell-like fluctuations, which can potentially contribute to investigating the active parameter effect on cell fluctuations.