Issue 3, 2023

Rapid and ultra-sensitive testosterone detection via aptamer-functional gold nanoparticles

Abstract

The capability to monitor doping in a rapid and sensitive manner is highly promising in the field of doping control. The point-of-care-testing (POCT) strategy can greatly meet the current requirements for doping detection. Testosterone is a typical doping agent in sporting events and is strictly prohibited by the World Anti-Doping Agency (WADA). Here, we report a POCT method based on aptamer-functional gold nanoparticles to detect testosterone (TES). The method provides sensitive detection of testosterone within minutes and its utility in real sample analysis has been demonstrated. Sensors based on an aptamer and gold nanoparticles exhibit good applications for rapid and ultra-sensitive testosterone detection and can be expanded to the monitoring of other doping agents.

Graphical abstract: Rapid and ultra-sensitive testosterone detection via aptamer-functional gold nanoparticles

Supplementary files

Article information

Article type
Communication
Submitted
31 Oct 2022
Accepted
30 Nov 2022
First published
14 Dec 2022

New J. Chem., 2023,47, 1023-1026

Rapid and ultra-sensitive testosterone detection via aptamer-functional gold nanoparticles

D. Zou, Y. Gu, D. Luo, W. Yang, R. Gao, X. Cao, W. Dong, H. Shi, H. Zhao and C. Liu, New J. Chem., 2023, 47, 1023 DOI: 10.1039/D2NJ05316K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements