Visible-light-promoted C(sp3)–H thiolation of aliphatic ethers with thiosulfonates

Wen-Zhu Bi; Qing-Pu Liu; Chen-Yu Li; Wen-Jie Zhang; Su-Xiang Feng; Yang Geng; Xiao-Lan Chen; Ling-Bo Qu

doi:10.1039/D3NJ01029E

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Visible-light-promoted C(sp³)–H thiolation of aliphatic ethers with thiosulfonates†

Wen-Zhu Bi,

*^ab Qing-Pu Liu,^a Chen-Yu Li,^a Wen-Jie Zhang,^a Su-Xiang Feng,*^bcd Yang Geng,*^e Xiao-Lan Chen

^f and Ling-Bo Qu^f

Author affiliations

* Corresponding authors

^a School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, China

^b Henan Engineering Research Center of Modern Chinese Medicine Research, Development and Application, Zhengzhou, China

^c Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, China
E-mail: fengsx221@163.com

^d Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P. R. China, Zhengzhou, China

^e Department of Pharmacy, Zhengzhou Railway Vocational and Technical College, Zhengzhou, China
E-mail: gengyang0001@163.com

^f College of Chemistry, Zhengzhou University, Zhengzhou, China

Abstract

A visible-light-promoted direct thiolation of α-C(sp³)–H in ethers with thiosulfonates was developed for the preparation of α-arylthioethers using easily availably Na₂-eosin Y and TBHP as a photocatalyst and oxidant. This reaction occurred smoothly under the irradiation of 5 W blue light at room temperature and generated the corresponding products in good to excellent yields.

This article is part of the themed collection: New Journal of Chemistry HOT Articles

Download options Please wait...

Supplementary files

Supplementary information PDF (6430K)

Article information

DOI: https://doi.org/10.1039/D3NJ01029E
Article type: Communication
Submitted: 03 Mar 2023
Accepted: 24 Apr 2023
First published: 24 Apr 2023

Download Citation

New J. Chem., 2023,47, 9035-9039

Permissions

Request permissions

Visible-light-promoted C(sp³)–H thiolation of aliphatic ethers with thiosulfonates

W. Bi, Q. Liu, C. Li, W. Zhang, S. Feng, Y. Geng, X. Chen and L. Qu, New J. Chem., 2023, 47, 9035 DOI: 10.1039/D3NJ01029E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

New Journal of Chemistry