One-pot cascade synthesis of dibenzothiophene-based heterobiaryls from dibenzothiophene-5-oxide

Abstract

A sulfoxide directed C–H metalation/boration/B₂Pin₂ mediated reduction/Suzuki coupling process to synthesize 4-substituted dibenzothiophene (DBT) in one-pot from dibenzothiophene-5-oxide (DBTO) was developed. A variety of DBT-based heterobiaryls were prepared in satisfactory to good yields. A mechanism was proposed. The application of this methodology was demonstrated by synthesizing a luminescent material.