Issue 7, 2023

Visible light-enabled alkylation of enol acetates with alkylboronic acids for the synthesis of α-alkyl ketones

Abstract

We have developed a visible-light-catalyzed alkylation reaction of alkylboronic acids with aromatic enol acetates to synthesize α-alkyl ketones. A variety of unsymmetrical ketones can be obtained in moderate to good yields under mild and simple conditions using alkyl boronic acids as alkylation reagents. In addition, a possible mechanism was proposed for this process.

Graphical abstract: Visible light-enabled alkylation of enol acetates with alkylboronic acids for the synthesis of α-alkyl ketones

Supplementary files

Article information

Article type
Research Article
Submitted
13 Jan 2023
Accepted
21 Feb 2023
First published
22 Feb 2023

Org. Chem. Front., 2023,10, 1710-1714

Visible light-enabled alkylation of enol acetates with alkylboronic acids for the synthesis of α-alkyl ketones

Y. Li, Z. Ma, X. Liu, Z. Li, F. Zhao and J. Wu, Org. Chem. Front., 2023, 10, 1710 DOI: 10.1039/D3QO00052D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements