Organophotoelectrochemical silylation cyclization for the synthesis of silylated 3-CF3-2-oxindoles

Abstract

An organophotoelectrochemical approach for silylation cyclization of CF₃-substituted N-arylacrylamides with organosilanes has been developed. This photoelectrochemical method uses 9,10-phenanthrenequinone (PQ) as both a catalyst and a hydrogen atom transfer (HAT) reagent, and organosilanes as silyl radical precursors, obviating the need for oxidants or metal reagents. A series of silylated 3-CF₃-2-oxindoles are prepared with satisfactory yields under simple and mild conditions.