Synthesis of a new magnetic metal organic framework based on nickel for extraction of carvacrol and thymol in thymus and savory samples and analyzed with gas chromatography

Abstract

The present research aims at reporting a new sorbent, a magnetic nano scale metal–organic framework (MOF), based on nickel acetate and 6-phenyl-1,3,5-triazine-2,4-diamine. The prepared sorbent was used to extract carvacrol and thymol using an ultrasonic-assisted dispersive micro solid phase extraction (UA-DμSPE) method. The structure of the metal organic framework was studied by applying scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), energy dispersive spectrometry (EDS), and vibrating sample magnetometer (VSM). The effects of various parameters such as ionic strength of sample solution, amount of sorbent (mg), volume of eluent solvent (μL), vortex and ultrasonic times (min) were optimized. Under optimal conditions, the analytes resulted in determination coefficients (R²) of 0.9985 and 0.9967 in the concentration range 0.01–2 μg mL⁻¹, and in limits of detection of 0.0025 and 0.0028 μg mL⁻¹. Significantly, this method can be successfully applied in order to determine the target analytes in spiked real samples. Notably, the relative mean recoveries range from 94.5 to 105.7%.