Eco-friendly and efficient catalyst-free synthesis of N-sulfonylimines from sulfonamides and aldehydes: crucial role of Al2O3 as a reusable dehydrating agent

Abstract

A green synthetic method for the synthesis of N-sulfonylimines was developed involving the straightforward condensation of sulfonamides with aldehydes under green and catalyst-free conditions, mediated by neutral Al₂O₃ as an efficient and reusable dehydrating agent. N-Sulfonylimines were produced in high yields and purity under simple experimental procedures.