Issue 18, 2024

Quantification of enantiomers and blind identification of erythro-sphingosine non-racemates by cold ion spectroscopy

Abstract

Enantiomers of a lipid erythro-sphingosine have been quantified with ≈4% accuracy by UV cold ion spectroscopy of their non-covalent complexes with a chiral aromatic molecule. The diastereomeric configuration of such complexes enables the quantification using just a single enantiomeric lipid standard and the identification of non-racemic solutions with no standards at all.

Graphical abstract: Quantification of enantiomers and blind identification of erythro-sphingosine non-racemates by cold ion spectroscopy

Supplementary files

Article information

Article type
Communication
Submitted
28 Jun 2024
Accepted
10 Aug 2024
First published
12 Aug 2024
This article is Open Access
Creative Commons BY license

Analyst, 2024,149, 4600-4604

Quantification of enantiomers and blind identification of erythro-sphingosine non-racemates by cold ion spectroscopy

V. Kopysov, R. Yamaletdinov and O. V. Boyarkin, Analyst, 2024, 149, 4600 DOI: 10.1039/D4AN00911H

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