Iridium-catalyzed selective arylation of B(6)–H of 3-aryl-o-carboranes with arylboronic acid via direct B–H activation†
Abstract
This work discloses an iridium-catalyzed selective arylation of B(6)–H of 3-Ar-o-carboranes with arylboronic acid via direct B–H activation for the first time. A series of unsymmetric and symmetric 3,6-diaryl-o-carboranes decorated with diverse active groups have been synthesized with moderate to excellent yields under mild conditions. This work offers an efficient approach for selective arylation of B(6)–H with arylboronic acid and has important value for selective functionalization of o-carboranes.
- This article is part of the themed collection: Chemical Communications HOT Articles 2024