Issue 61, 2024

Concise synthesis of chiral γ-butenolides via an allylation/lactonization cascade reaction

Abstract

A highly enantioselective allylation/lactonization cascade was developed, which provides a concise and efficient route to chiral γ-butenolides under mild conditions. Most of the reaction examples can be completed in 10 minutes with high selectivity.

Graphical abstract: Concise synthesis of chiral γ-butenolides via an allylation/lactonization cascade reaction

Supplementary files

Article information

Article type
Communication
Submitted
08 Jun 2024
Accepted
01 Jul 2024
First published
02 Jul 2024

Chem. Commun., 2024,60, 7926-7929

Concise synthesis of chiral γ-butenolides via an allylation/lactonization cascade reaction

Z. Tan, A. Yihuo, Z. Wu, F. Wang, S. Dong and X. Feng, Chem. Commun., 2024, 60, 7926 DOI: 10.1039/D4CC02781G

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