Identifying distinct noncanonical structures in pathogenic genomes is crucial for developing new diagnostic tools. This study uncovers stable G-quadruplex (GQ) structures in conserved DNA sequences unique to the monkeypox virus (MPV). Furthermore, we developed a method for the detection of target GQ using a fluorogenic probe.
S. Pratihar, R. Venkatesh, M. N. Mattath and T. Govindaraju, Chem. Commun., 2024, 60, 13004 DOI: 10.1039/D4CC03726J
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