Issue 6, 2024
From the journal:

Nanoscale

Janus mesoporous organosilica/platinum nanomotors for active treatment of suppurative otitis media†

Zhizhou Luo,a   Ruonan Wang,a   Xiaoxia Deng,a   Tianxiang Chen,bc   Xuehua Ma, ORCID logo bc   Yujie Zhang, ORCID logo *abc   Changyong Gao ORCID logo *abc  and  Aiguo Wu ORCID logo *bc  

* Corresponding authors

a Biomedical Research Institute, Wenzhou Medical University, Zhejiang 315300, China
E-mail: zhangyujie@nimte.ac.cn, gaochangyong@nimte.ac.cn

b Ningbo Key Laboratory of Biomedical Imaging Probe Materials and Technology, Zhejiang International Cooperation Base of Biomedical Materials Technology and Application, Chinese Academy of Sciences (CAS) Key Laboratory of Magnetic Materials and Devices, Zhejiang Engineering Research Center for Biomedical Materials at Ningbo Cixi Institute of Biomedical Engineering, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China
E-mail: aiguo@nimte.ac.cn

c University of Chinese Academy of Science, Beijing, China

Abstract

We report a Janus mesoporous organosilica/platinum (MOS/Pt) nanomotor for active targeted treatment of suppurative otitis media, as a new type of multi-functional ear drop. The efficient propulsion of MOS/Pt nanomotors in hydrogen peroxide ear-cleaning drops significantly improves their binding efficiency with Staphylococcus aureus and enhances their antibacterial efficacy.

Graphical abstract: Janus mesoporous organosilica/platinum nanomotors for active treatment of suppurative otitis media

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Article information

DOI
https://doi.org/10.1039/D3NR05666J
Article type
Paper
Submitted
08 Nov 2023
Accepted
29 Dec 2023
First published
02 Jan 2024

Nanoscale, 2024,16, 3006-3010

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Janus mesoporous organosilica/platinum nanomotors for active treatment of suppurative otitis media

Z. Luo, R. Wang, X. Deng, T. Chen, X. Ma, Y. Zhang, C. Gao and A. Wu, Nanoscale, 2024, 16, 3006 DOI: 10.1039/D3NR05666J

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