Issue 32, 2024

Exploring nanodiamonds: leveraging their dual capacities for anticancer photothermal therapy and temperature sensing

Abstract

Cancer has become a primary global health concern, which has prompted increased attention towards targeted therapeutic approaches like photothermal therapy (PTT). The unique optical and magnetic properties of nanodiamonds (NDs) have made them versatile nanomaterials with promising applications in biomedicine. This comprehensive review focuses on the potential of NDs as a multifaceted platform for anticancer therapy, mainly focusing on their dual functionality in PTT and temperature sensing. The review highlighted NDs’ ability to enhance PTT through hybridization or modification, underscoring their adaptability in delivering small molecule reagents effectively. Furthermore, NDs, particularly fluorescent nanodiamonds (FNDs) with negatively charged nitrogen-vacancy centers, enable precise temperature monitoring, enhancing PTT efficacy in anticancer treatment. Integrating FNDs into PTT holds promise for advancing therapeutic efficacy by providing valuable insights into localized temperature variations and cell death mechanisms. This review highlights new insights into cancer treatment strategies, showcasing the potential of NDs to revolutionize targeted therapeutics and improve patient outcomes.

Graphical abstract: Exploring nanodiamonds: leveraging their dual capacities for anticancer photothermal therapy and temperature sensing

Article information

Article type
Review Article
Submitted
12 Apr 2024
Accepted
15 Jul 2024
First published
24 Jul 2024

Nanoscale, 2024,16, 14994-15008

Exploring nanodiamonds: leveraging their dual capacities for anticancer photothermal therapy and temperature sensing

W. W. Hsiao, X. M. Lam, T. Le, C. Cheng and H. Chang, Nanoscale, 2024, 16, 14994 DOI: 10.1039/D4NR01615G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements