Issue 4, 2024

An aminobenzannulation reaction of a propargylic ester and isocyanides to access multi-functionalized aryl amine derivatives

Abstract

An aminobenzannulation of two molecular isocyanides and a propargylic ester has been reported. This reaction involves sequential annulation and rearrangement processes, providing efficient access to multi-substituted aniline and naphthylamine derivatives.

Graphical abstract: An aminobenzannulation reaction of a propargylic ester and isocyanides to access multi-functionalized aryl amine derivatives

Supplementary files

Article information

Article type
Research Article
Submitted
06 Dec 2023
Accepted
28 Dec 2023
First published
29 Dec 2023

Org. Chem. Front., 2024,11, 1192-1197

An aminobenzannulation reaction of a propargylic ester and isocyanides to access multi-functionalized aryl amine derivatives

Z. Ni, J. Hu, K. Yin, T. Chen, X. Li, L. Cui, C. Li and J. Li, Org. Chem. Front., 2024, 11, 1192 DOI: 10.1039/D3QO02011H

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