Electrochemical 1,5-chlorosulfonylation and 1,5-hydrosulfonylation of vinylcyclopropanes

Abstract

An electrochemical 1,5-chlorosulfonylation and 1,5-hydrosulfonylation of vinylcyclopropanes is presented. This protocol offers a broad substrate scope, high functional group tolerance, and excellent E/Z selectivity under mild conditions, without the need for oxidants, reductants, or transition metals. Additionally, the process is easily scalable to the gram scale. The resulting products are valuable intermediates for the synthesis of quinolinone derivatives. Mechanism studies have indicated the involvement of a short radical chain propagation.