The asymmetric synthesis of warfarin in microdroplets and thin films generated by an electrospray ionization (ESI) source is reported. This is one of the first examples of an enantioselective organocatalyzed reaction in electrosprayed confined volumes. The optimal conditions in terms of system setting were established for this reaction.
M. De Angelis, M. Managò, F. Pepi, C. Salvitti, A. Troiani, C. Villani and A. Ciogli, RSC Adv., 2024, 14, 1576 DOI: 10.1039/D3RA07975A
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