Enhancing continuous-flow reactions via compression-molding of solid catalysts and dilutants in packed-bed systems

Abstract

In this study, we present an improved packed-bed system designed for continuous-flow reactions using platinum (Pt)-black powder and silica gel (SiO₂). The Pt-leaching from the reaction column is suppressed via compression-molding of the Pt and SiO₂. Scanning electron microscopy results and particle-size distribution analysis demonstrate that crushed and downsized SiO₂ is effective in suppressing outflow. Furthermore, we successfully conducted a scaled-up experiment of the flow reaction using a large column, achieving excellent productivity.