A biocompatible cellulose gum based CMC/PVA/SBA-15 film as a colloidal antibacterial agent against MRSA

Abstract

The development of biocompatible antibacterial films plays a crucial role in the fight against antibiotic-resistant bacteria strains. Here, we developed an SBA-15–NH₂ decorated biocompatible CMC/PVA film containing Ag NPs as an antibacterial material against Gram-positive and Gram-negative bacteria strains. The structure of the manufactured film was studied by XRD, SEM, mapping, and TGA analysis showing its formation and firm structure. The prepared film has a flexible structure which makes it suitable for a variety of bio-related applications. The CMC/PVA/SBA-15–NH₂@AgNPs film was used as a bactericidal agent against pathogens (especially MRSA; methicillin-resistant Staphylococcus aureus) isolated from surgical site infections, showing promising results.