Issue 35, 2024

Deboronative functionalization of alkylboron species via a radical-transfer strategy

Abstract

With advances in organoboron chemistry, boron-centered functional groups have become increasingly attractive. In particular, alkylboron species are highly versatile reagents for organic synthesis, but the direct generation of alkyl radicals from commonly used, bench-stable boron species has not been thoroughly investigated. Herein, we describe a method for activating C–B bonds by nitrogen- or oxygen-radical transfer that is applicable to alkylboronic acids and esters and can be used for both Michael addition reactions and Minisci reactions to generate alkyl or arylated products.

Graphical abstract: Deboronative functionalization of alkylboron species via a radical-transfer strategy

Supplementary files

Article information

Article type
Edge Article
Submitted
01 May 2024
Accepted
07 Aug 2024
First published
08 Aug 2024
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2024,15, 14241-14247

Deboronative functionalization of alkylboron species via a radical-transfer strategy

F. Yue, M. Li, K. Yang, H. Song, Y. Liu and Q. Wang, Chem. Sci., 2024, 15, 14241 DOI: 10.1039/D4SC02889A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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