Issue 4, 2025
From the journal:

Chemical Communications

Facile in situ synthesis of silver nanoclusters for promoting highly sensitive surface-enhanced Raman scattering detection of alkyne-tagged biomolecules†

Leixin Hou, ORCID logo *a   Mi Zhang,a   Daofu Liu,a   Mai Xua  and  Huilin Huang*b  

* Corresponding authors

a School of Chemistry and Materials Engineering, Huainan Normal University, Huainan, Anhui, P. R. China

b School of Chemical and Printing Dyeing Engineering, Henan University of Engineering, Zhengzhou, P. R. China
E-mail: houleixin@hnnu.edu.cn, huangxiaoya1992@mail.dlut.edu.cn

Abstract

We synthesized two novel silver-based nanocluster materials (TOS-Ag4 NCs and TNS-Ag8 NCs) that were used as SERS substrates, combining the powerful adsorption capability and aggregation effect of silver–sulfur clusters to achieve a highly sensitive identification and detection of alkyne-tagged molecules in the Raman-silent region. This work provides new insights for designing novel nanoclusters as SERS substrates displaying ultrahigh sensitive detection of alkyne-tagged molecules.

Graphical abstract: Facile in situ synthesis of silver nanoclusters for promoting highly sensitive surface-enhanced Raman scattering detection of alkyne-tagged biomolecules

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Article information

DOI
https://doi.org/10.1039/D4CC04813J
Article type
Communication
Submitted
17 Sep 2024
Accepted
25 Nov 2024
First published
28 Nov 2024

Chem. Commun., 2025,61, 689-692

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Facile in situ synthesis of silver nanoclusters for promoting highly sensitive surface-enhanced Raman scattering detection of alkyne-tagged biomolecules

L. Hou, M. Zhang, D. Liu, M. Xu and H. Huang, Chem. Commun., 2025, 61, 689 DOI: 10.1039/D4CC04813J

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