Designing superoxide-responsive near-infrared afterglow materials for enhanced arthritis imaging

Abstract

Here we report an afterglow material, APT/TTQNPs. This material can be activated by superoxide anions (O₂˙⁻) to emit NIR afterglow. APT/TTQNPs possess high selectivity, high sensitivity, and high imaging signal-to-noise ratio to O₂˙⁻. We successfully use APT/TTQNPs for imaging LPS-induced arthritis in mice.