Issue 14, 2011
From the journal:

Chemical Communications

Hydrophilically stabilized gold nanostars as SERSlabels for tissue imaging of the tumor suppressor p63 by immuno-SERS microscopy†‡

Max Schütz,a   Dennis Steinigeweg,a   Mohammad Salehi,a   Karsten Kömpeb  and  Sebastian Schlücker*a  

* Corresponding authors

a University of Osnabrück, Department of Physics, Barbarastr. 7, 49069 Osnabrück, Germany
E-mail: sebastian.schluecker@uos.de
Fax: +49 541 969 13592
Tel: +49 541 969 3592

b University of Osnabrück, Institute of Chemistry, Barbarastr. 7, 49069 Osnabrück, Germany

Abstract

A biocompatible, seed-mediated synthesis of monodisperse ∼60 nm gold nanostars, followed by hydrophilic stabilization with ethylene glycol-modified Raman reporter molecules, is presented. Their application as SERS labels for imaging of the tumor suppressor p63 in prostate biopsies by immuno-SERS microscopy is demonstrated.

Graphical abstract: Hydrophilically stabilized gold nanostars as SERS labels for tissue imaging of the tumor suppressor p63 by immuno-SERS microscopy

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Article information

DOI
https://doi.org/10.1039/C0CC05229A
Article type
Communication
Submitted
27 Nov 2010
Accepted
10 Feb 2011
First published
28 Feb 2011

Chem. Commun., 2011,47, 4216-4218

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Hydrophilically stabilized gold nanostars as SERS labels for tissue imaging of the tumor suppressor p63 by immuno-SERS microscopy

M. Schütz, D. Steinigeweg, M. Salehi, K. Kömpe and S. Schlücker, Chem. Commun., 2011, 47, 4216 DOI: 10.1039/C0CC05229A

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