Issue 3, 2012

Highly enantioselective Friedel–Crafts alkylation reaction catalyzed by rosin-derived tertiary amine–thiourea: synthesis of modified chromanes with anticancer potency

Abstract

We present herein for the first time the synthesis and preliminary biological evaluation of various modified chromanesvia a rosin-derived tertiary amine–thiourea-catalyzed highly enantioselective Friedel–Crafts alkylation reaction.

Graphical abstract: Highly enantioselective Friedel–Crafts alkylation reaction catalyzed by rosin-derived tertiary amine–thiourea: synthesis of modified chromanes with anticancer potency

Supplementary files

Article information

Article type
Communication
Submitted
20 Jul 2011
Accepted
01 Nov 2011
First published
14 Nov 2011

Chem. Commun., 2012,48, 446-448

Highly enantioselective Friedel–Crafts alkylation reaction catalyzed by rosin-derived tertiary aminethiourea: synthesis of modified chromanes with anticancer potency

X. Jiang, L. Wu, Y. Xing, L. Wang, S. Wang, Z. Chen and R. Wang, Chem. Commun., 2012, 48, 446 DOI: 10.1039/C1CC14379D

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