Issue 73, 2012
From the journal:

Chemical Communications

Lab-chip HPLC with integrated droplet-based microfluidics for separation and high frequency compartmentalisation†‡

Jin-Young Kim,a   Soong-Won Cho,b   Dong-Ku Kang,c   Joshua B. Edel,b   Soo-Ik Chang,d   Andrew J. deMelloe  and  Danny O'Hare*a  

* Corresponding authors

a Department of Bioengineering, Imperial College London, London SW7 2AZ, UK
E-mail: d.ohare@imperial.ac.uk

b Department of Chemistry, Imperial College London, London SW7 2AZ, UK

c Department of Pharmaceutical Sciences, University of California, Irvine, USA

d Department of Biochemistry, Chungbuk National University, Cheongju, Korea

e Institute for Chemical and Bioengineering Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland

Abstract

We demonstrate the integration of a droplet-based microfluidic device with high performance liquid chromatography (HPLC) in a monolithic format. Sequential operations of separation, compartmentalisation and concentration counter were conducted on a monolithic chip. This describes the use of droplet-based microfluidics for the preservation of chromatographic separations, and its potential application as a high frequency fraction collector.

Graphical abstract: Lab-chip HPLC with integrated droplet-based microfluidics for separation and high frequency compartmentalisation

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2CC33774F
Article type
Communication
Submitted
25 May 2012
Accepted
23 Jul 2012
First published
24 Jul 2012

Chem. Commun., 2012,48, 9144-9146

Permissions

Request permissions

Lab-chip HPLC with integrated droplet-based microfluidics for separation and high frequency compartmentalisation

J. Kim, S. Cho, D. Kang, J. B. Edel, S. Chang, A. J. deMello and D. O'Hare, Chem. Commun., 2012, 48, 9144 DOI: 10.1039/C2CC33774F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements