Issue 21, 2013
From the journal:

Chemical Communications

Supramolecular hydrogels based on bola-amphiphilic glycolipids showing color change in response to glycosidases†‡

Rika Ochi,a   Kazuya Kurotani,a   Masato Ikeda,b   Shigeki Kiyonakaa  and  Itaru Hamachi*ac  

* Corresponding authors

a Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Kyoto, Japan
E-mail: ihamachi@sbchem.kyoto-u.ac.jp
Fax: +81-75-383-2759
Tel: +81-75-383-2754

b Department of Biomolecular Science, Graduate School of Engineering, United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, Gifu, Japan

c Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), 5 Sanbancho, Chiyoda-ku, Tokyo, Japan

Abstract

We developed supramolecular hydrogels exhibiting reversible thermochromism concurrently with gel-to-sol transition from four glycolipids. In addition, these gels showed the similar color change in response to glycosidases, which can be employed to construct a colorimetric sensor array chip for sensing glycosidases with the naked eye.

Graphical abstract: Supramolecular hydrogels based on bola-amphiphilic glycolipids showing color change in response to glycosidases

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Article information

DOI
https://doi.org/10.1039/C2CC37908B
Article type
Communication
Submitted
31 Oct 2012
Accepted
13 Dec 2012
First published
14 Dec 2012

Chem. Commun., 2013,49, 2115-2117

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Supramolecular hydrogels based on bola-amphiphilic glycolipids showing color change in response to glycosidases

R. Ochi, K. Kurotani, M. Ikeda, S. Kiyonaka and I. Hamachi, Chem. Commun., 2013, 49, 2115 DOI: 10.1039/C2CC37908B

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