Issue 6, 2015

Formal [3+2] cycloaddition of Ugi adducts towards pyrrolines

Abstract

Ugi adducts derived from aromatic aldehydes may be converted to pyrrolines via addition of Michael acceptors under microwave irradiation. The reaction may proceed via unusual formation of azomethine ylides followed by a [3+2] cycloaddition using Michael acceptors.

Graphical abstract: Formal [3+2] cycloaddition of Ugi adducts towards pyrrolines

Associated articles

Supplementary files

Article information

Article type
Communication
Submitted
20 Oct 2014
Accepted
26 Nov 2014
First published
26 Nov 2014

Chem. Commun., 2015,51, 1116-1119

Author version available

Formal [3+2] cycloaddition of Ugi adducts towards pyrrolines

A. Ben Abdessalem, R. Abderrahim, A. Agrebie, A. Dos Santos, L. El Kaïm and A. Komesky, Chem. Commun., 2015, 51, 1116 DOI: 10.1039/C4CC08282F

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