Omprakash
Bande
b,
Darren
Braddick
a,
Stefano
Agnello
b,
Miyeon
Jang
b,
Valérie
Pezo
a,
Guy
Schepers
b,
Jef
Rozenski
b,
Eveline
Lescrinier
b,
Philippe
Marlière
a and
Piet
Herdewijn
*ab
aiSSB – CNRS FRE3561, University of Evry-Val-d'Essonne, 5 rue Henri Desbruères, Genopole Campus 1, Bât. 6, F-91030 Évry Cedex, France. E-mail: piet.herdewijn@rega.kuleuven.be; Tel: +32 16 337387
bMedicinal Chemistry, Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium
First published on 11th December 2015
Correction for ‘Base pairing involving artificial bases in vitro and in vivo’ by Omprakash Bande et al., Chem. Sci., 2016, DOI: 10.1039/c5sc03474d.
Fig. 10 The in vivo interpretation of the 8-Oxo-dI nucleotide within the essential thyA gene. The normalized ratio is the experimentally derived average number of thymidine-prototrophic colonies (bla+ thyA+) from the average total number of colonies (bla+ thyA− and bla+ thyA+). The modified section of the oligomer sequence indicates the position of the 8-Oxo-dI nucleotide/s, for single (left) and double (right) codons.
Fig. 11 The in vivo interpretation of the 8-Oxo-dG nucleotide (top) and 8-Oxo-dA nucleotide (bottom) within the essential thyA gene. The normalized ratio is the experimentally derived average number of thymidine-prototrophic colonies (bla+ thyA+) from the average total number of colonies (bla+ thyA− and bla+ thyA+). The modified section of the oligomer sequence indicates the position of the 8-Oxo-dG and 8-Oxo-dA nucleotide/s.
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