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Correction: A versatile glycosylation strategy via Au(III) catalyzed activation of thioglycoside donors
Amol M.
Vibhute
,
Arun
Dhaka
,
Vignesh
Athiyarath
and
Kana M.
Sureshan
*
School of Chemistry, Indian Institute of Science Education and Research, Thiruvananthapuram, Kerala-695016, India. E-mail: kms@iisertvm.ac.in; Fax: +91 4712597427
First published on 2nd August 2016
Abstract
Correction for ‘A versatile glycosylation strategy via Au(III) catalyzed activation of thioglycoside donors’ by Amol M. Vibhute et al., Chem. Sci., 2016, 7, 4259–4263.
The authors wish to amend statements in the original article that concern the effectiveness of low quantities of AuX3 additive for thioglycoside activation. The use of 3–20 mol% AuX3 is reported in the original article. However, the authors have recently discovered that, at low AuX3 loading, the yield of glycosylation varied from trial-to-trial and depending on the source of AuX3. The yield also varied considerably depending on the time since the bottle of AuX3 had been opened, irrespective of its source. However, with higher AuX3 loading (0.8 equiv.), the reactions were reproducible in high yields across multiple attempts. As representative examples, the reactions in entries 8–10, 14, 17 and 26 were repeated with 0.8 equiv. of AuX3. In all of these cases, the yields of the glycosylation products were good (74–89%) with minor amounts of hydrolyzed products. For consistent and reproducible results, it is necessary to use 0.8 equiv. of AuX3.
Therefore, all references to AuX3 as a catalyst, or its use in catalytic amounts, should be disregarded throughout the original article and the following changes to the values presented in Tables 1 and 2 should be noted:
The reaction conditions given for the general reaction embedded in Table 1 should be corrected to the following: “ROH, AuCl3 (0.8 equiv.), CH2Cl2, 4 Å MS, rt”.
The footnote in Table 2 should be changed to the following: “a Reaction condition: donor (1.0 equiv.), acceptor (1.0 equiv.), CH2Cl2, AuCl3, 4 Å MS, rt. b Isolated by chromatography. c Calculated using NMR spectroscopy. d/e AuBr3 (0.8 equiv. of AuX3 was used).”
The authors apologise for these errors and any consequent inconvenience to editors and readers.
The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.
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