Oxidative cyclization of 2-allenyl-1,1′-biphenyls with α-carbonyl alkyl bromides: facile access to functionalized phenanthrenes

Abstract

A new copper-facilitated oxidative cyclization of 2-allenyl-1,1′-biphenyls with α-carbonyl alkyl bromides for producing functionalized phenanthrenes is presented, which represents the first allene 2,3-dicarbofunctionalization triggered by oxidative radical-medicated C3-addition of the terminal allene moiety and C–Br/C–H functionalization.