Issue 42, 2019

A small-molecule probe for ratiometric photoacoustic imaging of hydrogen sulfide in living mice

Abstract

A small-molecule photoacoustic probe based on cyanine dyes was developed by taking advantage of the nucleophilic substitution reaction of H2S with chlorine. The probe demonstrated specific response to H2S with ratiometric photoacoustic signals in the NIR region, which enabled real-time, accurate, high-resolution imaging of endogenous H2S in vivo.

Graphical abstract: A small-molecule probe for ratiometric photoacoustic imaging of hydrogen sulfide in living mice

Supplementary files

Article information

Article type
Communication
Submitted
20 Mar 2019
Accepted
26 Apr 2019
First published
26 Apr 2019

Chem. Commun., 2019,55, 5934-5937

A small-molecule probe for ratiometric photoacoustic imaging of hydrogen sulfide in living mice

X. Li, Y. Tang, J. Li, X. Hu, C. Yin, Z. Yang, Q. Wang, Z. Wu, X. Lu, W. Wang, W. Huang and Q. Fan, Chem. Commun., 2019, 55, 5934 DOI: 10.1039/C9CC02224D

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