Chirality transfer based on dynamic covalent chemistry: from small chiral molecules to supramolecules

Abstract

Single-tailed and gemini-type supra-gelators were facilely fabricated via the conjugation of the D- or L-enantiomeric dihydrazide TDH with single-tailed achiral aldehyde C₁₂BAD through dynamic acylhydrazone bonding. Chirality transfer from small molecules to supramolecules was successfully achieved via the spontaneous assembly of the formed supra-gelators into supramolecular chiral hydrogels.