Issue 25, 2020
From the journal:

Chemical Communications

Fluorinated cryptophane-A and porphyrin-based theranostics for multimodal imaging-guided photodynamic therapy†

Huaibin Zhang,ab   Qiao Yu,a   Yu Li,b   Zhigang Yang, ORCID logo a   Xin Zhou, ORCID logo b   Shizhen Chen*b  and  Zhong-Xing Jiang ORCID logo *a  

* Corresponding authors

a Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals and School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China
E-mail: zxjiang@whu.edu.cn

b State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovative Academy of Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China
E-mail: chenshizhen@wipm.ac.cn

Abstract

Herein, we developed fluorinated nanoemulsions with significantly enhanced in vitro and in vivo129Xe hyper-CEST MRI, 19F MRI and fluorescence imaging signals for selective and sensitive tumor detection and NIR-activated photodynamic therapy.

Graphical abstract: Fluorinated cryptophane-A and porphyrin-based theranostics for multimodal imaging-guided photodynamic therapy

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Article information

DOI
https://doi.org/10.1039/D0CC00694G
Article type
Communication
Submitted
26 Jan 2020
Accepted
20 Feb 2020
First published
21 Feb 2020

Chem. Commun., 2020,56, 3617-3620

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Fluorinated cryptophane-A and porphyrin-based theranostics for multimodal imaging-guided photodynamic therapy

H. Zhang, Q. Yu, Y. Li, Z. Yang, X. Zhou, S. Chen and Z. Jiang, Chem. Commun., 2020, 56, 3617 DOI: 10.1039/D0CC00694G

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