2-Azidoacrylamides as compact platforms for efficient modular synthesis

Hinano Takemura; Sayuri Goto; Takamitsu Hosoya; Suguru Yoshida

doi:10.1039/D0CC07212E

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

2-Azidoacrylamides as compact platforms for efficient modular synthesis†

Hinano Takemura,^a Sayuri Goto,^a Takamitsu Hosoya

^a and Suguru Yoshida

*^a

Author affiliations

* Corresponding authors

^a Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Tokyo 101-0062, Chiyoda-ku, Japan
E-mail: s-yoshida.cb@tmd.ac.jp

Abstract

Efficient methods to assemble modules with compact platform molecules by triazole formations and Michael reactions are disclosed. The good electrophilicity of 2-triazolylacrylamides realized Michael additions using various nucleophiles. An iterative synthesis of a tetrakis(triazole) was accomplished by orthogonal triazole formations and Michael reactions.

Download options Please wait...

Supplementary files

Supplementary information PDF (32135K)

Article information

DOI: https://doi.org/10.1039/D0CC07212E
Article type: Communication
Submitted: 31 Oct 2020
Accepted: 19 Nov 2020
First published: 19 Nov 2020

Download Citation

Chem. Commun., 2020,56, 15541-15544

Permissions

Request permissions

2-Azidoacrylamides as compact platforms for efficient modular synthesis

H. Takemura, S. Goto, T. Hosoya and S. Yoshida, Chem. Commun., 2020, 56, 15541 DOI: 10.1039/D0CC07212E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications

2-Azidoacrylamides as compact platforms for efficient modular synthesis†

Abstract

Supplementary files

Article information

Download Citation

Permissions

2-Azidoacrylamides as compact platforms for efficient modular synthesis

Social activity

Search articles by author

Spotlight

Advertisements