Issue 15, 2020

Oxidative cascade cyclization of 2-cyano-3-arylaniline derived acrylamides with toluenes, ethers, aliphatic alcohols or simple alkanes

Abstract

An oxidative radical cascade cyclization of 2-cyano-3-arylaniline derived acrylamides with hydrocarbons is described. The present reaction exhibits a wide substrate scope, and toluenes, ethers, aliphatic alcohols and simple alkanes can be employed as coupling partners, providing access to alkyl substituted pyrido[4,3,2-gh]phenanthridines.

Graphical abstract: Oxidative cascade cyclization of 2-cyano-3-arylaniline derived acrylamides with toluenes, ethers, aliphatic alcohols or simple alkanes

Supplementary files

Article information

Article type
Research Article
Submitted
08 May 2020
Accepted
16 Jun 2020
First published
16 Jun 2020

Org. Chem. Front., 2020,7, 1997-2002

Oxidative cascade cyclization of 2-cyano-3-arylaniline derived acrylamides with toluenes, ethers, aliphatic alcohols or simple alkanes

W. Xia, Y. Xin, Z. Zhao, X. Chen, X. Wang, Y. Li, G. Wang and Y. Li, Org. Chem. Front., 2020, 7, 1997 DOI: 10.1039/D0QO00535E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements