Retraction: TRIM22 functions as an oncogene in gliomas through regulating the Wnt/β-catenin signaling pathway

Abstract

Retraction of ‘TRIM22 functions as an oncogene in gliomas through regulating the Wnt/β-catenin signaling pathway’ by Shi-lei Tang et al., RSC Adv., 2018, 8, 30894–30901, DOI: 10.1039/C8RA05684F.

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The Royal Society of Chemistry hereby wholly retracts this RSC Advances article due to concerns with the reliability of the data. The images in the article were screened by an image integrity expert. The western blot bands may not be genuine. Furthermore, the western blots and many other features of the article were found to be unexpectedly similar to western blots and features in a number of other papers with no overlapping authors.

In addition, the paper was analysed by experts who fact-checked the identities of the described nucleotide sequence reagents,¹ and found errors with the following nucleotide sequence reagents reported in the article. The TRIM22 reverse primer is non-targeting and, therefore, the results shown in Fig. 2 are not reliable.

The authors were asked to provide the raw data for this article, but did not respond. Given the significance of the concerns about the validity of the data, and the lack of raw data, the findings presented in this paper are not reliable.

The authors have been informed but have not responded to any correspondence regarding the retraction.

Signed: Laura Fisher, Executive Editor, RSC Advances

Date: 15^th January 2021

References

1. C. Labbé, N. Grima, T. Gautier, B. Favier and J. A. Byrne, PLoS One, 2019, 14(3), e0213266.

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