Issue 34, 2022

A covalent organic framework with a self-contained light source for photodynamic therapy

Abstract

External light-independent antitumor PDT is successfully realized with a covalent organic framework (COF)-based host–guest nanosystem. Its highly effective antitumor behavior is fully demonstrated by both H2O2-overexpressed 4T1 and H2O2-less expressed HCT116 and MCF-7 xenograft models.

Graphical abstract: A covalent organic framework with a self-contained light source for photodynamic therapy

Supplementary files

Article information

Article type
Communication
Submitted
09 Mar 2022
Accepted
29 Mar 2022
First published
30 Mar 2022

Chem. Commun., 2022,58, 5245-5248

A covalent organic framework with a self-contained light source for photodynamic therapy

W. Ren, F. Kong, Y. Shao, Q. Huang, L. Sun, J. Feng and Y. Dong, Chem. Commun., 2022, 58, 5245 DOI: 10.1039/D2CC01397E

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